Tip:
All open tiddlers are refreshed (though not usually completely) on every user action. If you can limit the number of tiddlers in the browser DOM, your wiki will feel much faster.
@saqimtiaz has posted an experimental single tiddler layout here (I have not tried it yet).
In this discussion I’ve shown a way to extend the zoomin story view to dynamically fold all tiddlers that are not currently shown, so their contents is not rendered into the DOM. That made a BIG difference for me when having 10+ tiddlers open in the story river.