WebContainers run Node.js natively in your browser. Could it be usefull for tiddlywiki?

Very cool! You can click this link to get your own Node.js instance in your browser: Node.js (duplicated) - StackBlitz

In the console on the bottom, you can install TiddlyWiki, create a new TiddlyWiki, and listen on port 8080. TiddlyWiki opens on the right.

It doesn’t save any changes to the “disk”, though (wherever that is!). Maybe that can be figured out.