I am not sure what is your question, but if you mean you want to change the field value in billion tiddlers the Kookma Tiddler Commander is the way you can go in browser, no matter you use TW on Node.JS or as a single html.
Tiddler Commander works on bulk of tiddlers for many batch operations.
I’m not using any of these tools myself, but I think one might update a field value:
using a specially crafted bookmarklet. @TW_Tones might be of great help here, he often writes on bookmarklets here on talk.tiddlywiki.org
on node.js using node-red, which looks like an automation tool featuring treatments on files triggered by events. This tool has also been quoted here on talk.tiddlywiki.org, a search should give you some more information.