Hi @brandonholland, welcome to talk.tiddlywiki!!
I’m a Node-and-git user, something fairly similar to what @CasperBooWisdom is suggesting. But if trying to use git with your node server seems too complex, you might try for a simpler setup and skip Node altogether.
There are two main advantages to Node, as I see it, and they’re closely related. First, it stores the wiki as separate tiddler files. If, like me, you occasionally want to perform some transformations on your tiddlers outside of what TW gives you out of the box, then this is immensely helpful. I can operate on tiddler files rather than the whole wiki.
Second, it makes it easier to save backups as lists of small changes, and not as entire wikis. I do this with git, but there are other tools that could do the same thing. This is also made much easier by the multiple files when running Node.
But if these advantages are not important to you, then you can easily use a single-file wiki, served up from the filesystem or from any of the seventeen zillion tools that create a miniature web server from the file-system. Whenever you want a backup, you can simply copy the file to your backup storage location. The only downside I know to this style is that when you save changes from Tiddlywiki, the OS will suggest that you save your file as something like myWiki.html - Copy or myWiki.html - Copy 2 on Windows or myWiki.1.html, myWiki.2.html on *nix, and you will have to correct it every time to save as myWiki.html every time. I don’t find that a big deal, but it is a minor inconvenience.
